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DRD4 Rabbit pAb

Anti-DRD4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219734

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219734
Product Name:   Anti-DRD4 Rabbit Polyclonal Antibody
Synonyms:   D4DR
UNIPROT ID:   P21917 (Gene Accession – NP_000788 )
Background:    This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.
Immunogen:    Synthetic peptide of human DRD4
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 20-May;WB: 500-1000;ELISA: 500-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 219734(DRD4 Antibody) at a dilution of 1/5(Cytoplasm, Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the synthetic peptide and then with 219734(Anti-DRD4 Antibody) at dilution 1/5.

Gel: 10%SDS-PAGE, Lysate: 30 μg;
Lane: Mouse skeletal muscle tissue;
Primary antibody: 219734(DRD4 Antibody) at dilution 1/350;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 minute
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