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IGFBP3 Rabbit pAb

Anti-IGFBP3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219860

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219860
Product Name:   Anti-IGFBP3 Rabbit Polyclonal Antibody
Synonyms:   IBP3; BP-53
UNIPROT ID:   P17936 (Gene Accession – NP_000589 )
Background:    This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Immunogen:    Synthetic peptide of human IGFBP3
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer, Metabolism, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 219860(IGFBP3 Antibody) at a dilution of 1/45(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 219860(Anti-IGFBP3 Antibody) at dilution 1/45.

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 219860(Anti-IGFBP3 Antibody) at a dilution of 1/45.

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with synthetic peptide and then with D260507(Anti-IGFBP3 Antibody) at dilution 1/45.
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