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IL3RA Rabbit pAb

Anti-IL3RA Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219865

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219865
Product Name:   Anti-IL3RA Rabbit Polyclonal Antibody
Synonyms:   IL3R; CD123; IL3RX; IL3RY; IL3RAY; hIL-3Ra
UNIPROT ID:   P26951 (Gene Accession – NP_002174 )
Background:    The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found.
Immunogen:    Synthetic peptide of human IL3RA
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 219865(IL3RA Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 219865(Anti-IL3RA Antibody) at dilution 1/50.

The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 219865(Anti-IL3RA Antibody) at a dilution of 1/50.

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with synthetic peptide and then with D260513(Anti-IL3RA Antibody) at dilution 1/50.
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