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KLK2 Rabbit pAb

Anti-KLK2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219876

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219876
Product Name:   Anti-KLK2 Rabbit Polyclonal Antibody
Synonyms:   hK2, hGK-1, KLK2A2
UNIPROT ID:   P20151 (Gene Accession – NP_005542 )
Background:    This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants.
Immunogen:    Synthetic peptide of human KLK2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 219876(KLK2 Antibody) at a dilution of 1/100(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 219876(Anti-KLK2 Antibody) at dilution 1/100.

The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 219876(Anti-KLK2 Antibody) at a dilution of 1/100.

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with synthetic peptide and then with D260535(Anti-KLK2 Antibody) at dilution 1/100.
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