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ITGAX Rabbit pAb

Anti-ITGAX Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219899

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219899
Product Name:   Anti-ITGAX Rabbit Polyclonal Antibody
Synonyms:   CD11C, SLEB6
UNIPROT ID:   P20702 (Gene Accession – NP_000878 )
Background:    This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles.
Immunogen:    Synthetic peptide of human ITGAX
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 15-50; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Immunology, Stem Cells
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 219899(ITGAX Antibody) at a dilution of 1/15(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 219899(Anti-ITGAX Antibody) at dilution 1/15.

The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 219899(Anti-ITGAX Antibody) at a dilution of 1/15.

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with synthetic peptide and then with D260573(Anti-ITGAX Antibody) at dilution 1/15.
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