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TOP1MT Rabbit pAb

Anti-TOP1MT Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220009

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220009
Product Name:   Anti-TOP1MT Rabbit Polyclonal Antibody
Synonyms:   
UNIPROT ID:   Q969P6 (Gene Accession – NP_001245375 )
Background:    This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Immunogen:    Synthetic peptide of human TOP1MT
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-May; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gasrtic cancer tissue using 220009(TOP1MT Antibody) at a dilution of 1/10(Cytoplasm, Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human gasrtic cancer tissue is first treated with the synthetic peptide and then with 220009(Anti-TOP1MT Antibody) at dilution 1/10.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 220009(Anti-TOP1MT Antibody) at a dilution of 1/10.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with synthetic peptide and then with D260774(Anti-TOP1MT Antibody) at dilution 1/10.
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