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AFDN Rabbit pAb

Anti-AFDN Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220094

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220094
Product Name:   Anti-AFDN Rabbit Polyclonal Antibody
Synonyms:   AF6; MLLT4; MLL-AF6; l-afadin
UNIPROT ID:   P55196 (Gene Accession – NP_001035089 )
Background:    This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t(6;11)(q27;q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.
Immunogen:    Synthetic peptide of human AFDN
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colon cancer tissue using 220094(AFDN Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with the synthetic peptide and then with 220094(Anti-AFDN Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 220094(Anti-AFDN Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with synthetic peptide and then with D260947(Anti-AFDN Antibody) at dilution 1/40.
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