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NPY1R Rabbit pAb

Anti-NPY1R Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220151

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220151
Product Name:   Anti-NPY1R Rabbit Polyclonal Antibody
Synonyms:   NPYR; NPY1-R
UNIPROT ID:   P25929 (Gene Accession – NP_000900 )
Background:    This gene belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity.
Immunogen:    Synthetic peptide of human NPY1R
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 220151(NPY1R Antibody) at a dilution of 1/20(Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the synthetic peptide and then with 220151(Anti-NPY1R Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 220151(Anti-NPY1R Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with synthetic peptide and then with D261046(Anti-NPY1R Antibody) at dilution 1/20.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: Human fetal brain tissue lysate;
Primary antibody: 220151(NPY1R Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 minute
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