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NQO1 Rabbit pAb

Anti-NQO1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220152

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220152
Product Name:   Anti-NQO1 Rabbit Polyclonal Antibody
Synonyms:   DTD; QR1; DHQU; DIA4; NMOR1; NMORI
UNIPROT ID:   P15559 (Gene Accession – NP_000894 )
Background:    This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein’s enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer’s disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Immunogen:    Synthetic peptide of human NQO1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 1000-5000;ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human liver cancer tissue using 220152(NQO1 Antibody) at a dilution of 1/25(Cytoplasm).

Immunohistochemistry analysis of paraffin-embedded Human lung cancer tissue using 220152(Anti-NQO1 Antibody) at a dilution of 1/25.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-4: Hela, MCF7, A549, HepG2 cell lysates;
Primary antibody: 220152(NQO1 Antibody) at dilution 1/600;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 1 second
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