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EIF2AK2 Rabbit pAb

Anti-EIF2AK2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220177

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220177
Product Name:   Anti-EIF2AK2 Rabbit Polyclonal Antibody
Synonyms:   PKR, PRKR, EIF2AK1
UNIPROT ID:   P19525 (Gene Accession – NP_002750 )
Background:    The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene
Immunogen:    Synthetic peptide of human EIF2AK2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 220177(EIF2AK2 Antibody) at a dilution of 1/60(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 220177(Anti-EIF2AK2 Antibody) at dilution 1/60.
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