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SFRP1 Rabbit pAb

Anti-SFRP1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220198

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220198
Product Name:   Anti-SFRP1 Rabbit Polyclonal Antibody
Synonyms:   FRP; FRP1; FrzA; FRP-1; SARP2
UNIPROT ID:   Q8N474 (Gene Accession – NP_003003.3 )
Background:    This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.
Immunogen:    Synthetic peptide of human SFRP1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 100-300; ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology, Neuroscience, Signal Transduction, Developmental Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 220198(SFRP1 Antibody) at a dilution of 1/80(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 220198(Anti-SFRP1 Antibody) at dilution 1/80.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 220198(Anti-SFRP1 Antibody) at a dilution of 1/80.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with synthetic peptide and then with D261118(Anti-SFRP1 Antibody) at dilution 1/80.
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