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STEAP4 Rabbit pAb

Anti-STEAP4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220214

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220214
Product Name:   Anti-STEAP4 Rabbit Polyclonal Antibody
Synonyms:   TIARP; STAMP2; SchLAH; TNFAIP9
UNIPROT ID:   Q687X5 (Gene Accession – NP_001192244 )
Background:    The protein encoded by this gene belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+), using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011]
Immunogen:    Synthetic peptide of human STEAP4
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 40-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 220214(STEAP4 Antibody) at a dilution of 1/45(Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the synthetic peptide and then with 220214(Anti-STEAP4 Antibody) at dilution 1/45.
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