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TNXB Rabbit pAb

Anti-TNXB Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220224

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220224
Product Name:   Anti-TNXB Rabbit Polyclonal Antibody
Synonyms:   XB; TNX; XBS; EDS3; HXBL; TENX; TN-X; TNXB1; TNXB2; TNXBS
UNIPROT ID:   P22105 (Gene Accession – NP_061978 )
Background:    This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5′ and 3′ ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Synthetic peptide of human TNXB
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 3000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human ovarian cancer tissue using 220224(TNXB Antibody) at a dilution of 1/30(Secreted, ExtraCellular space, ExtraCellular matrix).

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with the synthetic peptide and then with 220224(Anti-TNXB Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 220224(Anti-TNXB Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with synthetic peptide and then with D261165(Anti-TNXB Antibody) at dilution 1/30.
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