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TGFBR1 Rabbit pAb

Anti-TGFBR1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220229

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220229
Product Name:   Anti-TGFBR1 Rabbit Polyclonal Antibody
Synonyms:   AAT5; ALK5; MSSE; SKR4; ALK-5; LDS1A; LDS2A; TGFR-1; ACVRLK4
UNIPROT ID:   P36897 (Gene Accession – NP_001124388 )
Background:    The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Synthetic peptide of human TGFBR1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 100-300; ELISA: 5000-20000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer, Cardiovascular, Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gasrtic cancer tissue using 220229(TGFBR1 Antibody) at a dilution of 1/70(Cytoplasm, Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human gasrtic cancer tissue is first treated with the synthetic peptide and then with 220229(Anti-TGFBR1 Antibody) at dilution 1/70.
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