Email: info@neweastbio.com   |  Call: 6109452007

TEK Rabbit pAb

Anti-TEK Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220232

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220232
Product Name:   Anti-TEK Rabbit Polyclonal Antibody
Synonyms:   TIE2; VMCM; TIE-2; VMCM1; CD202B
UNIPROT ID:   Q02763 (Gene Accession – NP_000450 )
Background:    The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.
Immunogen:    Synthetic peptide of human TEK
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer, Cardiovascular, Stem Cells, Developmental Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 220232(TEK Antibody) at a dilution of 1/40(Cytoplasm ).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 220232(Anti-TEK Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 220232(Anti-TEK Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with synthetic peptide and then with D261174(Anti-TEK Antibody) at dilution 1/40.
          Publications