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ACO2 Rabbit pAb

Anti-ACO2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220261

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220261
Product Name:   Anti-ACO2 Rabbit Polyclonal Antibody
Synonyms:   ICRD; ACONM
UNIPROT ID:   Q99798 (Gene Accession – NP_001089 )
Background:    The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.
Immunogen:    Synthetic peptide of human ACO2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 220261(ACO2 Antibody) at a dilution of 1/30(Cytoplasm, Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 220261(Anti-ACO2 Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 220261(Anti-ACO2 Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with synthetic peptide and then with D261224(Anti-ACO2 Antibody) at dilution 1/30.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: Mouse heart tissue, hela cells;
Primary antibody: 220261(ACO2 Antibody) at dilution 1/400;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 3 seconds
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