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ARHGEF6 Rabbit pAb

Anti-ARHGEF6 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220301

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220301
Product Name:   Anti-ARHGEF6 Rabbit Polyclonal Antibody
Synonyms:   PIXA; COOL2; MRX46; Cool-2; alphaPIX; alpha-PIX
UNIPROT ID:   Q15052 (Gene Accession – NP_004831 )
Background:    Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation.
Immunogen:    Synthetic peptide of human ARHGEF6
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 220301(ARHGEF6 Antibody) at a dilution of 1/70(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the synthetic peptide and then with 220301(Anti-ARHGEF6 Antibody) at dilution 1/70.
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