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RCAN1 Rabbit pAb

Anti-RCAN1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220319

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220319
Product Name:   Anti-RCAN1 Rabbit Polyclonal Antibody
Synonyms:   CSP1; DSC1; RCN1; DSCR1; MCIP1; ADAPT78
UNIPROT ID:   P53805 (Gene Accession – NP_004405 )
Background:    The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene.
Immunogen:    Synthetic peptide of human RCAN1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 220319(RCAN1 Antibody) at a dilution of 1/45(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 220319(Anti-RCAN1 Antibody) at dilution 1/45.

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 220319(Anti-RCAN1 Antibody) at a dilution of 1/45.

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with synthetic peptide and then with D261343(Anti-RCAN1 Antibody) at dilution 1/45.

Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: Mouse heart tissue, Mouse brain tissue;
Primary antibody: 220319(RCAN1 Antibody) at dilution 1/500;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 minute
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