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NRG2 Rabbit pAb

Anti-NRG2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220328

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220328
Product Name:   Anti-NRG2 Rabbit Polyclonal Antibody
Synonyms:   DON1; HRG2; NTAK
UNIPROT ID:   O14511 (Gene Accession – NP_001171864 )
Background:    This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described.
Immunogen:    Synthetic peptide of human NRG2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-300; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 220328(NRG2 Antibody) at a dilution of 1/65(Secreted).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 220328(Anti-NRG2 Antibody) at dilution 1/65.

The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 220328(Anti-NRG2 Antibody) at a dilution of 1/65.

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with synthetic peptide and then with D261359(Anti-NRG2 Antibody) at dilution 1/65.
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