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NLRP7 Rabbit pAb

Anti-NLRP7 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220380

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220380
Product Name:   Anti-NLRP7 Rabbit Polyclonal Antibody
Synonyms:   HYDM; PAN7; NALP7; NOD12; PYPAF3; CLR19.4
UNIPROT ID:   Q8WX94 (Gene Accession – NP_001120727 )
Background:    This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunogen:    Synthetic peptide of human NLRP7
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 100-300; ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gasrtic cancer tissue using 220380(NLRP7 Antibody) at a dilution of 1/60(Cytoplasm or Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human gasrtic cancer tissue is first treated with the synthetic peptide and then with 220380(Anti-NLRP7 Antibody) at dilution 1/60.

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 220380(Anti-NLRP7 Antibody) at a dilution of 1/60.

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with synthetic peptide and then with D261456(Anti-NLRP7 Antibody) at dilution 1/60.
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