Email: info@neweastbio.com   |  Call: 6109452007

PTPRC Rabbit pAb

Anti-PTPRC Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220441

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220441
Product Name:   Anti-PTPRC Rabbit Polyclonal Antibody
Synonyms:   LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180
UNIPROT ID:   P08575 (Gene Accession – NP_002829 )
Background:    The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling.
Immunogen:    Synthetic peptide of human PTPRC
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 100-300; ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Neuroscience, Cardiovascular, Immunology, Stem Cells
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human Lymphoma tissue using 220441(PTPRC Antibody) at a dilution of 1/60(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human Lymphoma tissue is first treated with the synthetic peptide and then with 220441(Anti-PTPRC Antibody) at dilution 1/60.

The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 220441(Anti-PTPRC Antibody) at a dilution of 1/60.

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with synthetic peptide and then with D261533(Anti-PTPRC Antibody) at dilution 1/60.
          Publications