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CR1 Rabbit pAb

Anti-CR1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220473

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220473
Product Name:   Anti-CR1 Rabbit Polyclonal Antibody
Synonyms:   KN; C3BR; C4BR; CD35
UNIPROT ID:   P17927 (Gene Accession – NP_000564 )
Background:    This gene is a member of the receptors of complement activation (RCA) family and is located in the ‘cluster RCA’ region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis.
Immunogen:    Synthetic peptide of human CR1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Immunology, Stem Cells
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 220473(CR1 Antibody) at a dilution of 1/25(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 220473(Anti-CR1 Antibody) at dilution 1/25.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 220473(Anti-CR1 Antibody) at a dilution of 1/25.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with synthetic peptide and then with D261579(Anti-CR1 Antibody) at dilution 1/25.
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