Email: info@neweastbio.com   |  Call: 6109452007

CSTB Rabbit pAb

Anti-CSTB Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220489

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220489
Product Name:   Anti-CSTB Rabbit Polyclonal Antibody
Synonyms:   PME; ULD; CST6; EPM1; STFB; EPM1A
UNIPROT ID:   P04080 (Gene Accession – NP_000091 )
Background:    The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes.
Immunogen:    Synthetic peptide of human CSTB
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 200-1000;ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 220489(CSTB Antibody) at a dilution of 1/30(Cytoplasm and Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the synthetic peptide and then with 220489(Anti-CSTB Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 220489(Anti-CSTB Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with synthetic peptide and then with D261602(Anti-CSTB Antibody) at dilution 1/30.

Gel: 10+12%SDS-PAGE, Lysate: 40 μg;
Lane: Mouse spleen tissue;
Primary antibody: 220489(CSTB Antibody) at dilution 1/300;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 2.5 minutes
          Publications