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DICER1 Rabbit pAb

Anti-DICER1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220508

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220508
Product Name:   Anti-DICER1 Rabbit Polyclonal Antibody
Synonyms:   DCR1; MNG1; Dicer; HERNA; RMSE2
UNIPROT ID:   Q9UPY3 (Gene Accession – NP_085124 )
Background:    This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.
Immunogen:    Synthetic peptide of human DICER1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 220508(DICER1 Antibody) at a dilution of 1/25(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 220508(Anti-DICER1 Antibody) at dilution 1/25.

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 220508(Anti-DICER1 Antibody) at a dilution of 1/25.

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with synthetic peptide and then with D261624(Anti-DICER1 Antibody) at dilution 1/25.
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