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CASP8AP2 Rabbit pAb

Anti-CASP8AP2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220552

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220552
Product Name:   Anti-CASP8AP2 Rabbit Polyclonal Antibody
Synonyms:   CED-4; FLASH; RIP25
UNIPROT ID:   Q9UKL3 (Gene Accession – NP_036247 )
Background:    This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.
Immunogen:    Synthetic peptide of human CASP8AP2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 220552(CASP8AP2 Antibody) at a dilution of 1/20(Cytoplasm and Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the synthetic peptide and then with 220552(Anti-CASP8AP2 Antibody) at dilution 1/20.
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