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IGF2R Rabbit pAb

Anti-IGF2R Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220620

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220620
Product Name:   Anti-IGF2R Rabbit Polyclonal Antibody
Synonyms:   MPR1; MPRI; CD222; CIMPR; M6P-R
UNIPROT ID:   P11717 (Gene Accession – NP_000867 )
Background:    This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.
Immunogen:    Synthetic peptide of human IGF2R
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 220620(IGF2R Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 220620(Anti-IGF2R Antibody) at dilution 1/40.
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