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NLRP10 Rabbit pAb

Anti-NLRP10 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220751

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220751
Product Name:   Anti-NLRP10 Rabbit Polyclonal Antibody
Synonyms:   NOD8; PAN5; PYNOD; NALP10; CLR11.1
UNIPROT ID:   Q86W26 (Gene Accession – NP_789791 )
Background:    Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein comple,x the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.
Immunogen:    Synthetic peptide of human NLRP10
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colon cancer tissue using 220751(NLRP10 Antibody) at a dilution of 1/45(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with the synthetic peptide and then with 220751(Anti-NLRP10 Antibody) at dilution 1/45.

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 220751(Anti-NLRP10 Antibody) at a dilution of 1/45.

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with synthetic peptide and then with D261961(Anti-NLRP10 Antibody) at dilution 1/45.
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