NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: S220764 | ||||
Product Name: Anti-DCAF6 Rabbit Polyclonal Antibody | ||||
Synonyms: NRIP; ARCAP; IQWD1; PC326; MSTP055; 1200006M05Rik | ||||
UNIPROT ID: Q58WW2 (Gene Accession – NP_001017977 ) | ||||
Background: NRIP (Nuclear receptor interaction protein), also known as IQWD1 ( IQ motif and WD repeat-containing protein 1), MSTP055, ARCAP or PC326, is an 860 amino acid protein that localizes to the nucleus and contains one IQ domain and seven WD-repeats. Expressed in testis, skeletal muscle, prostate and heart, NRIP functions as a ligand-dependent coactivator of nuclear receptors and specifically enhances the transcriptional activity of AR (androgen receptor) and GR (glucocorticoid receptor). NRIP exists as three isoforms that are produced by alternative splicing events. | ||||
Immunogen: Synthetic peptide of human DCAF6 | ||||
Applications: ELISA, IHC | ||||
Recommended Dilutions: IHC: 50-200; ELISA: 2000-5000 | ||||
Host Species: Rabbit | ||||
Clonality: Rabbit Polyclonal | ||||
Isotype: Immunogen-specific rabbit IgG | ||||
Purification: Antigen affinity purification | ||||
Species Reactivity: Human, Mouse | ||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||
Research Areas: Signal Transduction, Epigenetics and Nuclear Signaling | ||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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