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SH2D3A Rabbit pAb

Anti-SH2D3A Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220765

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220765
Product Name:   Anti-SH2D3A Rabbit Polyclonal Antibody
Synonyms:   NSP1
UNIPROT ID:   Q9BRG2 (Gene Accession – NP_005481 )
Background:    SH2D3A (SH2 domain containing 3A), also known as novel SH2-containing protein 1, is a 576 amino acid protein that is thought to play a role in JNK activation. SH2D3A interacts with p130 Cas and is found at low levels in fetal kidney, fetal lung, placenta, adult pancreas, kidney and lung. Subject to post-translational phosphorylation on multiple tyrosine residues, SH2D3A contains one Src homology 2 (SH2) domain. SH2 domains bind to tyrosine-phosphorylated regions of target proteins, frequently linking activated growth factors to putative signal transduction proteins.
Immunogen:    Synthetic peptide of human SH2D3A
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 220765(SH2D3A Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the synthetic peptide and then with 220765(Anti-SH2D3A Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 220765(Anti-SH2D3A Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with synthetic peptide and then with D261980(Anti-SH2D3A Antibody) at dilution 1/40.
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