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PER2 Rabbit pAb

Anti-PER2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220796

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220796
Product Name:   Anti-PER2 Rabbit Polyclonal Antibody
Synonyms:   FASPS; FASPS1
UNIPROT ID:   O15055 (Gene Accession – NP_073728 )
Background:    This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic Nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders.
Immunogen:    Synthetic peptide of human PER2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 100-300; ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Epigenetics and Nuclear Signaling, Neuroscience, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 220796(PER2 Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 220796(Anti-PER2 Antibody) at dilution 1/50.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 220796(Anti-PER2 Antibody) at a dilution of 1/50.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with synthetic peptide and then with D262035(Anti-PER2 Antibody) at dilution 1/50.
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