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PLEC Rabbit pAb

Anti-PLEC Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220815

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220815
Product Name:   Anti-PLEC Rabbit Polyclonal Antibody
Synonyms:   HD1; PCN; EBS1; EBSO; PLTN; PLEC1; LGMD2Q; PLEC1b
UNIPROT ID:   Q15149 (Gene Accession – NP_000436 )
Background:    Plectin is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking different elements of the cytoskeleton. Plakins, with their multi-domain structure and enormous size, not only play crucial roles in maintaining cell and tissue integrity and orchestrating dynamic changes in cytoarchitecture and cell shape, but also serve as scaffolding platforms for the assembly, positioning, and regulation of signaling complexes.
Immunogen:    Synthetic peptide of human PLEC
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 220815(PLEC Antibody) at a dilution of 1/40(Cytoplasm and Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 220815(Anti-PLEC Antibody) at dilution 1/40.
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