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PLXNA4 Rabbit pAb

Anti-PLXNA4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220819

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220819
Product Name:   Anti-PLXNA4 Rabbit Polyclonal Antibody
Synonyms:   PLEXA4; PLXNA4A; PLXNA4B; FAYV2820; PRO34003
UNIPROT ID:   Q9HCM2 (Gene Accession – NP_001099013 )
Background:    Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.
Immunogen:    Synthetic peptide of human PLXNA4
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 220819(PLXNA4 Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 220819(Anti-PLXNA4 Antibody) at dilution 1/50.
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