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RASA3 Rabbit pAb

Anti-RASA3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220848

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220848
Product Name:   Anti-RASA3 Rabbit Polyclonal Antibody
Synonyms:   GAPIII; GAP1IP4BP
UNIPROT ID:   Q14644 (Gene Accession – NP_031394 )
Background:    The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2.
Immunogen:    Synthetic peptide of human RASA3
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 30-150; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 220848(RASA3 Antibody) at a dilution of 1/35(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 220848(Anti-RASA3 Antibody) at dilution 1/35.

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 220848(Anti-RASA3 Antibody) at a dilution of 1/35.

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with synthetic peptide and then with D262112(Anti-RASA3 Antibody) at dilution 1/35.
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