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SIGLEC7 Rabbit pAb

Anti-SIGLEC7 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220908

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220908
Product Name:   Anti-SIGLEC7 Rabbit Polyclonal Antibody
Synonyms:   p75; QA79; AIRM1; CD328; CDw328; D-siglec; SIGLEC-7; SIGLECP2; SIGLEC19P; p75/AIRM1
UNIPROT ID:   Q9Y286 (Gene Accession – NP_055200 )
Background:    Siglec-7, which is highly expressed in monocytes and resident blood cells but not in parenchymatous cells, mediates inhibition of natural killer cell cytotoxicity. Due to alternative splicing events, two isoforms exist for Siglec-12, namely SLG-L (the long isoform) and SLG-S (the shorter isoform). These isoforms are differentially expressed with the longer isoform predominantly found in small intestine, spleen and bone marrow, and the shorter isoform predominantly found in small intestine, spleen and adrenal gland.
Immunogen:    Synthetic peptide of human SIGLEC7
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience, Cardiovascular, Immunology, Stem Cells
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 220908(SIGLEC7 Antibody) at a dilution of 1/35(Cytoplasm or Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 220908(Anti-SIGLEC7 Antibody) at dilution 1/35.

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 220908(Anti-SIGLEC7 Antibody) at a dilution of 1/35.

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with synthetic peptide and then with D262201(Anti-SIGLEC7 Antibody) at dilution 1/35.
          Publications