Email: info@neweastbio.com   |  Call: 6109452007

SLC41A2 Rabbit pAb

Anti-SLC41A2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220931

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220931
Product Name:   Anti-SLC41A2 Rabbit Polyclonal Antibody
Synonyms:   SLC41A1-L1
UNIPROT ID:   Q96JW4 (Gene Accession – NP_115524 )
Background:    SLC41A2 (solute carrier family 41, member 2), also known as SLC41A1-L, is a 573 amino acid multi-pass membrane protein that belongs to the SLC41A transporter family that includes SLC41A1 and SLC41A3. Expressed in lymphocytes and localizing to the cell membrane, SLC41A2 contains twelve transmembrane domains, three myristoylation sequences, numerous possible phosphorylation sites and a putative N-glycosylation site. SLC41A2 is believed to function as a plasma-membrane magnesium transporter. Magnesium, a cofactor for ATP, plays a vital role in metabolic and biochemical processes. The transport of magnesium across membranes is essential for maintaining magnesium homeostasis and is fundamental to vertebrate metabolism.
Immunogen:    Synthetic peptide of human SLC41A2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 20-100;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 220931(SLC41A2 Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 220931(Anti-SLC41A2 Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 220931(Anti-SLC41A2 Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with synthetic peptide and then with D262242(Anti-SLC41A2 Antibody) at dilution 1/20.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-3: Human lung cancer tissue, Human lung adenocarcinoma tissue, Human liver cancer tissue lysates;
Primary antibody: 220931(SLC41A2 Antibody) at dilution 1/250;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 4 minutes
          Publications