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SNTA1 Rabbit pAb

Anti-SNTA1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220991

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220991
Product Name:   Anti-SNTA1 Rabbit Polyclonal Antibody
Synonyms:   SNT1; LQT12; TACIP1; dJ1187J4.5
UNIPROT ID:   Q13424 (Gene Accession – NP_003089 )
Background:    Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes.
Immunogen:    Synthetic peptide of human SNTA1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 200-1000;ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 220991(SNTA1 Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 220991(Anti-SNTA1 Antibody) at dilution 1/20.

Gel: 8%SDS-PAGE, Lysate: 80 μg;
Lane 1-2: Human colon cancer and normal stomach tissue;
Primary antibody: 220991(SNTA1 Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 minute
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