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TRPM6 Rabbit pAb

Anti-TRPM6 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221056

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221056
Product Name:   Anti-TRPM6 Rabbit Polyclonal Antibody
Synonyms:   HSH; HMGX; HOMG; CHAK2; HOMG1
UNIPROT ID:   Q9BX84 (Gene Accession – NP_060132 )
Background:    This gene is predominantly expressed in the kidney and colon, and encodes a protein containing an ion channel domain and a protein kinase domain. It is crucial for magnesium homeostasis, and plays an essential role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Mutations in this gene are associated with hypomagnesemia with secondary hypocalcemia. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Immunogen:    Synthetic peptide of human TRPM6
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Signal Transduction, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 221056(TRPM6 Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 221056(Anti-TRPM6 Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 221056(Anti-TRPM6 Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with synthetic peptide and then with D262419(Anti-TRPM6 Antibody) at dilution 1/20.
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