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CHD3 Rabbit pAb

Anti-CHD3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221086

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221086
Product Name:   Anti-CHD3 Rabbit Polyclonal Antibody
Synonyms:   ZFH; Mi-2a; SNIBCPS; Mi2-ALPHA
UNIPROT ID:   Q12873 (Gene Accession – NP_001005273 )
Background:    This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Immunogen:    Synthetic peptide of human CHD3
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 221086(CHD3 Antibody) at a dilution of 1/50(Nucleus and Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the synthetic peptide and then with 221086(Anti-CHD3 Antibody) at dilution 1/50.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 221086(Anti-CHD3 Antibody) at a dilution of 1/50.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with synthetic peptide and then with D262456(Anti-CHD3 Antibody) at dilution 1/50.
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