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GDF10 Rabbit pAb

Anti-GDF10 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221242

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221242
Product Name:   Anti-GDF10 Rabbit Polyclonal Antibody
Synonyms:   BIP; BMP3B; BMP-3b
UNIPROT ID:   P55107 (Gene Accession – NP_004953 )
Background:    This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This promotes neural repair after stroke. Additionally, this protein may act as a tumor suppressor and reduced expression of this gene is associated with oral cancer.
Immunogen:    Synthetic peptide of human GDF10
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-50; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer, Stem Cells
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 221242(GDF10 Antibody) at a dilution of 1/30(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the synthetic peptide and then with 221242(Anti-GDF10 Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 221242(Anti-GDF10 Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with synthetic peptide and then with D262756(Anti-GDF10 Antibody) at dilution 1/30.
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