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TRPV6 Rabbit pAb

Anti-TRPV6 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221259

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221259
Product Name:   Anti-TRPV6 Rabbit Polyclonal Antibody
Synonyms:   CAT1; CATL; ZFAB; ECAC2; ABP/ZF; LP6728; HSA277909
UNIPROT ID:   Q9H1D0 (Gene Accession – NP_061116 )
Background:    This gene encodes a member of a family of multipass membrane proteins that functions as calcium channels. The encoded protein contains N-terminal ankyrin repeats, which are required for channel assembly and regulation. Translation initiation for this protein occurs at a non-AUG start codon that is decoded as methionine. This gene is situated next to a closely related gene for transient receptor potential cation channel subfamily V member 5 (TRPV5). This locus has experienced positive selection in non-African populations, resulting in several non-synonymous codon differences among individuals of different genetic backgrounds.
Immunogen:    Synthetic peptide of human TRPV6
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 221259(TRPV6 Antibody) at a dilution of 1/25(Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 221259(Anti-TRPV6 Antibody) at dilution 1/25.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 221259(Anti-TRPV6 Antibody) at a dilution of 1/25.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with synthetic peptide and then with D262775(Anti-TRPV6 Antibody) at dilution 1/25.
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