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CHRNA6 Rabbit pAb

Anti-CHRNA6 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221286

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221286
Product Name:   Anti-CHRNA6 Rabbit Polyclonal Antibody
Synonyms:   CHNRA6
UNIPROT ID:   Q15825 (Gene Accession – NP_004189 )
Background:    This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence.
Immunogen:    Synthetic peptide of human CHRNA6
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: Oct-50; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 221286(CHRNA6 Antibody) at a dilution of 1/25(Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 221286(Anti-CHRNA6 Antibody) at dilution 1/25.

The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 221286(Anti-CHRNA6 Antibody) at a dilution of 1/25.

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with synthetic peptide and then with D262811(Anti-CHRNA6 Antibody) at dilution 1/25.
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