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ACKR3 Rabbit pAb

Anti-ACKR3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221408

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221408
Product Name:   Anti-ACKR3 Rabbit Polyclonal Antibody
Synonyms:   RDC1; CXCR7; RDC-1; CMKOR1; CXC-R7; CXCR-7; GPR159
UNIPROT ID:   P25106 (Gene Accession – NP_064707 )
Background:    This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq, Jul 2008]
Immunogen:    Synthetic peptide of human ACKR3
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 221408(ACKR3 Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 221408(Anti-ACKR3 Antibody) at dilution 1/50.
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