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IQGAP1 Rabbit pAb

Anti-IQGAP1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221445

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221445
Product Name:   Anti-IQGAP1 Rabbit Polyclonal Antibody
Synonyms:   SAR1; p195; HUMORFA01
UNIPROT ID:   P46940 (Gene Accession – NP_003861 )
Background:    This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.
Immunogen:    Synthetic peptide of human IQGAP1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 221445(IQGAP1 Antibody) at a dilution of 1/25(Cytoplasm and Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the synthetic peptide and then with 221445(Anti-IQGAP1 Antibody) at dilution 1/25.

The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 221445(Anti-IQGAP1 Antibody) at a dilution of 1/25.

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with synthetic peptide and then with D263039(Anti-IQGAP1 Antibody) at dilution 1/25.
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