Email: info@neweastbio.com   |  Call: 6109452007

CENPF Rabbit pAb

Anti-CENPF Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221495

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221495
Product Name:   Anti-CENPF Rabbit Polyclonal Antibody
Synonyms:   CENF; hcp-1; CILD31; PRO1779
UNIPROT ID:   P49454 (Gene Accession – NP_057427 )
Background:    This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease.
Immunogen:    Synthetic peptide of human CENPF
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: Oct-50; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 221495(CENPF Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the synthetic peptide and then with 221495(Anti-CENPF Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 221495(Anti-CENPF Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with synthetic peptide and then with D263116(Anti-CENPF Antibody) at dilution 1/20.
          Publications