NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: S221534 | ||||
Product Name: Anti-YPEL5 Rabbit Polyclonal Antibody | ||||
Synonyms: CGI-127 | ||||
UNIPROT ID: P62699 (Gene Accession – NP_057145 ) | ||||
Background: YPEL5 (yippee-like 5), also known as CGI-127, is a 121 amino acid protein that may be involved in cell division-related function. During cell cycle progression, YPEL5 localizes to multiple subcellular regions. At interphase of mitosis, YPEL5 localizes to the nucleus and centrosome, then changes its location sequentially to the spindle poles, mitotic spindle and spindle midzone, and finally it is transferred to the midbody at cytokinesis. The function of YPEL5 during cell division is not yet fully understood. | ||||
Immunogen: Synthetic peptide of human YPEL5 | ||||
Applications: ELISA, IHC | ||||
Recommended Dilutions: IHC: Oct-50; ELISA: 5000-10000 | ||||
Host Species: Rabbit | ||||
Clonality: Rabbit Polyclonal | ||||
Isotype: Immunogen-specific rabbit IgG | ||||
Purification: Antigen affinity purification | ||||
Species Reactivity: Human, Mouse | ||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||
Research Areas: Cell Biology | ||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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