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NSD2 Rabbit pAb

Anti-NSD2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221550

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221550
Product Name:   Anti-NSD2 Rabbit Polyclonal Antibody
Synonyms:   WHS; TRX5; KMT3F; KMT3G; MMSET; WHSC1; REIIBP
UNIPROT ID:   O96028 (Gene Accession – NP_579877 )
Background:    This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG bo,x a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences. [provided by RefSeq, Jul 2008]
Immunogen:    Synthetic peptide of human NSD2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 221550(NSD2 Antibody) at a dilution of 1/40(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the synthetic peptide and then with 221550(Anti-NSD2 Antibody) at dilution 1/40.
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