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UNC5B Rabbit pAb

Anti-UNC5B Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221586

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221586
Product Name:   Anti-UNC5B Rabbit Polyclonal Antibody
Synonyms:   UNC5H2; p53RDL1
UNIPROT ID:   Q8IZJ1 (Gene Accession – NP_734465 )
Background:    This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene.
Immunogen:    Synthetic peptide of human UNC5B
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 221586(UNC5B Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 221586(Anti-UNC5B Antibody) at dilution 1/50.
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