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CDC14B Rabbit pAb

Anti-CDC14B Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221703

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221703
Product Name:   Anti-CDC14B Rabbit Polyclonal Antibody
Synonyms:   CDC14B3; Cdc14B1; Cdc14B2; hCDC14B
UNIPROT ID:   O60729 (Gene Accession – NP_201588 )
Background:    The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.
Immunogen:    Synthetic peptide of human CDC14B
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gastric cancer tissue using 221703(CDC14B Antibody) at a dilution of 1/20(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with the synthetic peptide and then with 221703(Anti-CDC14B Antibody) at dilution 1/20.
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