Email: info@neweastbio.com   |  Call: 6109452007

COL17A1 Rabbit pAb

Anti-COL17A1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221760

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221760
Product Name:   Anti-COL17A1 Rabbit Polyclonal Antibody
Synonyms:   ERED; BP180; BPA-2; BPAG2; LAD-1; BA16H23.2
UNIPROT ID:   Q9UMD9 (Gene Accession – NP_000485 )
Background:    This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form.
Immunogen:    Synthetic peptide of human COL17A1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 221760(COL17A1 Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the synthetic peptide and then with 221760(Anti-COL17A1 Antibody) at dilution 1/50.

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 221760(Anti-COL17A1 Antibody) at a dilution of 1/50.

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with synthetic peptide and then with D263493(Anti-COL17A1 Antibody) at dilution 1/50.
          Publications