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PMP22 Rabbit pAb

Anti-PMP22 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221777

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221777
Product Name:   Anti-PMP22 Rabbit Polyclonal Antibody
Synonyms:   DSS; CIDP; GAS3; HNPP; CMT1A; CMT1E; GAS-3; Sp110; HMSNIA
UNIPROT ID:   Q01453 (Gene Accession – NP_000295 )
Background:    This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Immunogen:    Synthetic peptide of human PMP22
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 221777(PMP22 Antibody) at a dilution of 1/35(Cytoplasm and Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 221777(Anti-PMP22 Antibody) at dilution 1/35.
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